N-PILL contains Norethisterone, a synthetic form of the natural hormone progesterone. It is widely prescribed to treat and manage menstrual disorders, irregular bleeding, endometriosis, and to postpone menstruation when medically necessary.
Norethisterone works by mimicking the effects of progesterone, a hormone essential for regulating the menstrual cycle and maintaining the normal functioning of the female reproductive system. By maintaining hormonal balance, N-PILL provides reliable control over menstrual timing and helps manage heavy or painful bleeding effectively.
This medication is a trusted choice among gynaecologists for its high efficacy, predictable results, and safety profile in treating hormonal and menstrual irregularities.
Mechanism of Action
Norethisterone acts as a progestogen, working by modifying the growth and shedding pattern of the uterine lining (endometrium). During the menstrual cycle, progesterone prepares the endometrium for the possible implantation of a fertilised egg.
By supplementing this hormone, N-PILL:
- Stabilises the endometrial lining, preventing irregular or heavy bleeding.
- Delays ovulation, thus allowing control over the timing of menstruation.
- Counteracts the effects of excess estrogen on the uterus.
- Provides symptomatic relief in hormonal imbalance-related disorders such as premenstrual syndrome (PMS) and endometriosis.
The controlled release of Norethisterone ensures consistent hormone levels in the bloodstream, providing predictable menstrual regulation.
Indications for Use
N-PILL (Norethisterone Tablets I.P. 10mg) is indicated for the following conditions:
- Menstrual irregularities such as delayed, frequent, or prolonged periods
- Dysfunctional uterine bleeding (non-structural causes)
- Endometriosis aims to reduce pelvic pain and endometrial tissue growth
- Premenstrual syndrome (PMS) to relieve mood changes, bloating, and breast tenderness
- Postponement of menstruation for special occasions or medical reasons
- Secondary amenorrhea (absence of menstruation due to hormonal imbalance)
Dosage and Administration
The medicine must only be used as prescribed, or it may lead to a serious condition. Some of the recommended dosages of N-pill are
- The usual dosage is 5–10 mg (one tablet) taken once or twice daily, as prescribed by the physician.
- For postponing menstruation, it is generally started 3 days before the expected onset of the period and continued for the desired duration.
- For menstrual disorders, treatment duration and dosage vary based on the condition and patient response.
- Tablets should be swallowed whole with water and taken at the same time each day.
- Do not discontinue abruptly without consulting a doctor.
Possible Side Effects
Usually, N-PILL is a well-tolerated medication; however, some individuals may experience mild side effects, such as:
- Nausea or vomiting
- Breast tenderness
- Headache or dizziness
- Fluid retention or bloating
- Mood swings
- Changes in menstrual flow or spotting
- Rarely, allergic rash or mild weight changes
Most side effects are temporary and resolve once the body adjusts to the medication. If they persist, contact your doctor immediately.
Precautions
To use the medicine effectively and without any unwanted side effects, certain precautions must be followed.
- Use only under medical supervision.
- Not recommended during pregnancy or while breastfeeding.
- Patients with a history of thrombosis, liver disease, or hormone-sensitive cancers should avoid use.
- Caution in diabetic or hypertensive patients.
- Do not use it as a contraceptive, as it does not prevent ovulation consistently.
Storage Instruction
Store it in a cool and dry place
Keep away from direct sunlight and from the reach of children
Check for the original packaging if it is broken, do not use it.