NOFLAM TABLET

Diclofenac Potassium and Paracetamol tablet is a combination of two medicines: Diclofenac and Paracetamol, commonly used in the management of pain, inflammation, and fever. This combination is also used to treat various other conditions, such as headaches, mild migraines, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, or painful menstruation. Paracetamol is an analgesic and antipyretic medication used to temporarily relieve mild to moderate pain and fever.

At the same time, Diclofenac Potassium is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing the production of prostaglandins. Take it with food to avoid getting an upset stomach.This combination is frequently prescribed in conditions where single-agent therapy may not provide sufficient relief, such as musculoskeletal disorders, post-operative pain, dental pain, headache, and dysmenorrhea.

Zoic Life Sciences is among the fastest-growing Pharmaceutical companies in India. It has been accredited by the ISO 9001:2008, WHO, GMP, and FDI specialized agencies. They are the leading manufacturer and supplier of high-quality Diclofenac Potassium and Paracetamol tablets marketed under the brand name Noflam. Collaborate with Zoic Lifesciences for PCD Pharma Franchise Business opportunities. 

What is the Working Mechanism of Diclofenac Potassium and Paracetamol tablets?

The Working Mechanism of the Diclofenac Potassium and Paracetamol tablet has been discussed in detail as follows: 

Diclofenac Potassium: It works by inhibiting the cyclooxygenase (COX) enzymes. These enzymes are responsible for the synthesis of prostaglandins, which are the chemical mediators involved in pain, inflammation, and fever. Hence, by reducing the prostaglandin production, diclofenac alleviates pain, reduces swelling, and decreases inflammatory responses.

Paracetamol: It acts as a mild pain reducer and antipyretic, enhancing Diclofenac’s pain relief action by acting on the hypothalamic heat-regulating center. It primarily works in the central nervous system by inhibiting a variant of the COX enzyme. 

When taken together, diclofenac and paracetamol can provide a more comprehensive approach to pain relief than any of the drugs alone.

Medical Benefits of Using Diclofenac Potassium and Paracetamol Tablets

A list of Medical Benefits of using Diclofenac Potassium and Paracetamol Tablets has  been mentioned as follows: 

Fever and Body Aches: It is effectively used to provide relief from fever and body aches. 

Musculoskeletal Pain: Effective in conditions like arthritis, osteoarthritis, rheumatoid arthritis, and spondylitis.

Post-operative and Post-traumatic Pain: Provides relief after surgical procedures, fractures, sprains, or soft tissue injuries.

Headache and Migraine: The combination is useful in controlling moderate to severe headaches.

Dental Pain: Often prescribed following dental procedures such as extractions or root canals.

Dysmenorrhea: Helps reduce uterine cramp-related pain. (Menstrual Cramps)

Possible Side Effects of Using Diclofenac Potassium and Paracetamol Tablets

Like all medications, this combination may cause adverse effects, especially with long-term or high-dose use. If these side effects persist, immediately consult your doctor or healthcare provider. 

A list of Side Effects has been mentioned as follows: 

• Nausea
• Vomiting
• Diarrhea
• Flatulence
• Headache
• Vertigo
• Dyspepsia
• Abdominal pain
• Decreased appetite
• Increased transaminase levels in the blood
• Rashes

General Safety and Precautions

Some Precautions and safety measures have to be followed while taking this medication. Disclose your previous or recent health issues to your healthcare provider. A list of precaution has been mentioned as follows: 

• Doses should not exceed recommended limits, as paracetamol overdose can cause serious liver damage.
• Long-term use should be monitored with regular liver and kidney function tests.
• This medication should be avoided in patients with peptic ulcer disease, severe liver or kidney impairment, or hypersensitivity to NSAIDs or paracetamol.
• Pregnant and breastfeeding women should take it only under medical supervision.

Frequently Asked Questions (FAQ’s)

• Can the use of Diclofenac and Paracetamol cause nausea and vomiting?

Yes, the use of Diclofenac and Paracetamol can cause nausea and vomiting. Taking it with milk, food, or with antacids can prevent nausea.

• Can the use of Diclofenac and Paracetamol cause damage to the kidneys?

Yes, the long-term use of Diclofenac and Paracetamol can cause damage to the kidneys.

• How should I take this tablet?

Take the tablet by mouth with water, preferably after meals to avoid stomach upset. Follow the dose and duration prescribed by your doctor. 

4. Can I take this with other painkillers?

Avoid taking it with other NSAIDs (like ibuprofen, aspirin, or naproxen) or medicines containing paracetamol, as it may increase the risk of side effects.