Paracetamol 500mg and Domperidone- The medication is a combination of two medicines: Doperidone and Paracetamol. It is used to cure migraines. It works by controlling chemical messengers and increasing gut movement helps food pass faster.The combination medicine helps manage common migraines effectively.
Domperidone focuses on the region in the brain that controls vomiting. It also enhances the movement of stomach and intestines that allows food to move easily through the stomach. Hence, the medication prevents nausea and vomiting in migraines. The combination medicine helps manage common migraines effectively. Also, do not crush or chew the tablets, take them as whole.
Zoic Lifesciences is a trusted manufacturer of Paracetamol 500mg and Domperidone tablets under the brand name Dompar tablet.
Mechanism of Paracetamol and Domperidone Tablets
Paracetamol serves as analgesic (which is known to be called pain reliever) and antipyretic(fever reducer). It mainly works in the central nervous system by inhibiting the synthesis of chemical messengers called prostaglandins which are responsible for transmitting pain signals and raising body temperature.
Domperidone blocks dopamine receptors in the chemoreceptor trigger zone in the brain, the area which is responsible for nausea and vomiting. It enhances the movement of stomach and intestines which helps food and medication move through the digestive system quickly. Therefore it improves absorption of paracetamol and helps relieve vomiting and bloating.
Benefits of Paracetamol and Domperidone Tablets
The following are the medicinal benefits of Paracetamol and Domperidone tablets:
- Paracetamol blocks pain causing chemical messengers and helps relieve migraine pain and fever.
- Domperidone blocks dopamine receptors in the brain and enhances gut movement to stop sickness.
- By stopping vomiting , Domperidone assures Paracetamol will stay for enough time in the stomach to get relief from pain.
- The medication provides faster symptom relief since doperidone improves gastric emptying and paracetamol gets absorbed faster.
Side Effects of Paracetamol and Domperidone Tablets
Though there are numerous benefits of Paracetamol and Domperidone tablets, after prolonged consumption, you may notice a few side effects. Some of the side effects of Paracetamol and Domperidone tablets include:
- Diarrhoea or Constipation
- Anxiety
- Abdominal pain or DIscomfort
- Dizziness
- Dry Mouth
If you notice any of these side effects, then visit your doctor ASAP. Do not delay the process as it may be life-threatening for you. Your doctor may examine you and look for other alternatives to Paracetamol and Domperidone tablets.
Precautions of Paracetamol and Domperidone Tablets
Some Precautions and safety measures have to be followed when using Paracetamol and Domperidone Tablets. Disclose your previous or recent health issues to your healthcare provider.
A list of precautions has been mentioned as follows:
- Do not exceed the recommended dose by your doctor. The maximum daily dose for adults should not be more than 4000mg.
- Avoid alcohol consumption while taking these tablets as alcohol increases the risk of liver damage.
- Domperidone is related to a higher risk with heart problems and cardiac arrest. The risk is even higher in elderly people of over 60 years old.
- If you have or have had any liver or kidney disease in the past, inform your doctor as the Paracetamol and Domperidone tablets may react.
- Avoid taking this combination medication or consult your healthcare provider if you’re pregnant or breastfeeding.
Frequently Asked Questions
1.Are the vital ingredients in Dompar Tablet formulated per Indian Pharmacopeia (IP) standards?
The combination medicines marketed in India including Dompar Tablet follows Indian regulatory requirements for active pharmaceutical ingredients like Paracetamol and Domperidone, assuring the medication obeys to pharmacopeial standards approved in the country.
2.Does Zoic Lifesciences follow quality standards in manufacturing Dompar Tablet?
Zoic Lifesciences produces its pharmaceutical products, including Domperidone-Paracetamol tablets, under regulated manufacturing practices and internal quality systems to comply with pharmaceutical quality norms for safety.
3.Is there batch-to-batch consistency in the composition of Dompar Tablets?
Yes,pharmaceutical products like Dompar Tablet are manufactured with robust quality control processes so that the active components’ strength and purity remain consistent across production batches.
4. Can the inactive ingredients vary between batches of Dompar Tablet?
While the active medicines (Paracetamol and Domperidone) remain standardized, inactive excipients (binders, fillers, coatings) may vary slightly between batches but are always pharmaceutical-grade and approved for use in tablet formulations.
5.Are there any special storage conditions for maintaining the composition of Dompar Tablet?
To preserve chemical stability, Dompar Tablet should be stored in a cool, dry place, protected from direct sunlight and moisture.
6.Does Zoic Lifesciences perform stability testing on Dompar Tablet?
As part of pharma quality practices, stability testing under controlled conditions is performed to ensure that the composition (especially Paracetamol and Domperidone) remains stable throughout the product’s shelf life.
7.Are there known formulation differences between Dompar Tablet and other brands of Paracetamol + Domperidone tablets?
While the active components are the same across different brands, formulation techniques, excipients, and coating technologies may vary between manufacturers, which can influence things like tablet disintegration time but not the core action.