PREGUARD-300 SR TAB

Natural Micronised Progesterone- Progesterone is a female hormone. Progesterone(Natural Micronised) is used to replenish hormones that the body doesn’t produce enough of ,most commonly to treat symptoms of menopause. It is also used for female infertility. It effectively treats pregnancy related issues caused by hormonal imbalance. It should be consumed at the same time everyday to gain the maximum benefit. You should continue consuming it as long as your doctor has prescribed for you even if you start feeling well soon. If you have a medical history of breast cancer , unusual bleeding in vagina or liver disease then inform your doctor in advance. You will go through several tests before and during the treatment. Also tell your doctor about what other medicines you are taking as they might be affected by these tablets.

Mechanism of Natural Micronised Progesterone:

Progesterone enters into cells and binds to intracellular progesterone receptors(PR-A and PR-B) situated in the nucleus. After binding, the progesterone-receptor complex forms a transcription factor. This complex binds to progesterone response elements(PREs) on DNA. It balances gene transcription that results in endometrial transition to secretory phase, preparation of uterine lining for implantation, reduction of uterine contractility and support for early pregnancy. As a result we have stabilized endometrium, improved implantation and maintained pregnancy.

Progesterone also acts through cell-surface receptors and intracellular signaling systems that do not need changes in gene transcription. This results in quick reduction  of uterine irritability and contraction frequency.

Progesterone is processed into allopregnanolone , a potent GABA-A receptor modulator. It has a calming , sedative and mood-stabilizing effect.

Benefits of Natural Micronised Progesterone:

The following are the medicinal benefits of Natural Micronised Progesterone tablets:

• Hormone Replacement Therapy(HRT): Natural Micronised Progesterone helps manage menopause symptoms like hot flashes , night sweats and mood swings. 

• Fertility and Pregnancy Support: It is very crucial in maintaining fertility and pregnancy support.

• Miscarriage Prevention: If a woman has a history of frequent miscarriage, NMP supplements can help maintain the pregnancy and increase the live birth rate.

• • Infertility Treatment: It is also used in assisted reproductive technologies like IVF and IUI to increase the chances of successful pregnancy. 
  • Preterm Birth Prevention: Progesterone helps relax the uterus and can significantly reduce the risk of preterm birth.

• Irregular Menstrual Cycles: NMP helps regulate irregular periods and restore menstruation in women.
• Neurological Effects: It can also have calming and neuroprotective effects.

Side Effects of Natural Micronised Progesterone:

Though there are numerous benefits of Natural Micronised Progesterone tablets, after prolonged consumption, you may notice a few side effects. Some of the side effects of NMP tablets include:

• Vomiting
• Vaginal yeast infection
• Abdominal pain
• Nausea
• Abnormal vaginal bleeding
• Bloating
• Breast pain
• Headache
• Swelling

If you notice any of these side effects, do visit your doctor ASAP. 

Safety measures and Precautions:

Before consuming Natural Micronised Progesterone  tablets, you should be mindful of a few things. When taken carefully, you can lead to a speedy recovery in your condition. Some of the precautions are:

• Alcohol: Avoid alcohol and smoking while taking these tablets.

• Pregnancy: The tablets are safe to use during pregnancy as they didn’t have any impact on the developing baby.

• Breast Feeding: The NMP supplements are absolutely safe to use during breastfeeding. They do not pass into the breastmilk and hence are not harmful for the baby.
• Driving: The tablets may decrease alertness, cause blurriness or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
• Dosage: Take this medicine as a whole. Do not chew, crush or break it.